To compare the growth differences between sea urchin hybrid families and evaluate the parents' combining ability in body weight, 42 hybrid families were produced. Using the restricted maximum likelihood and best linear unbiased prediction approaches, the breeding value of body weight at 250, 295, and 340 days of age, the general combining ability (GCA) of male and female parents and the specific combining ability (SCA) of parental combinations were evaluated. Differences in the phenotypic value and breeding value of body weight among families were compared using variance analysis. The results showed that both the phenotypic and breeding values of body weight significantly differed among families (<0.01). The breeding value of body weight showed a greater variation among families than the phenotypic value. When the proportion of the selected families was 50%, 88.89%-94.44% of the selected families were identical between the phenotypic and breeding value selection methods, and the breeding value selection method had a 0.93%-4.83% better selection efficiency. At the ages of 250, 295, and 340 days, the calculated GCAs of the male parents were -0.22-0.33, -0.31-0.41, and -0.29-0.31 whereas those of the female parents were -0.24-0.33, -0.31-0.41, and -0.28-0.28, respectively. The calculated SCAs of the parental combinations were -0.07-0.09, -0.10-0.13, and -0.32-0.32. At the ages of 250, 295, and 340 days, the male parents M5, M6, and M17 and the female parents F9, F11, and F19 always had higher GCAs than the other parents. The parental combinations M5F9 and M6F11 always had higher SCAs than the other combinations. The results provide a reference point for progeny testing and family selection in hybrid families.