, a fast growth and commercially valuable marine fish species with better tolerance to cold water temperature than most other grouper species, is considered as one of the most potential species for the marine fish cage culture in the temperature seas along the coast of Northeast Asia. It has been being investigated intensively for aquaculture during the past several decades in the distributed countries including China, Japan and Korea. However, the stable and efficient artificial breeding technique has not been established fully for itowning to some reproduction problems such as extended maturation age for male, failure to spawn spontaneously under captivity and the fragility of newly hatched larvae. The progress on the broodstock reproduction, larval rearing, and the nursery of juveniles of seven-band grouper, which is achieved mainly by Japanese scientists during the past twenty years, is reviewed. Further research priorities in this domain are also suggested. This paper also provides the necessary referential information for the research on the mass seed production technique of seven-band grouper being in progress in China.