饲料中添加重组抗菌肽对吉富罗非鱼生长性能及免疫力的影响

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饲料中添加重组抗菌肽对吉富罗非鱼生长性能及免疫力的影响
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作者单位:1. 中国科学院 海洋研究所, 2. 中国科学院 研究生院,
作者简介:姜珊 (1983-), 女, 博士研究生, 研究方向为水产病害防治. E-mail: jiangshan.foru@163.com
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中图分类号:S943
基金项目:国家863计划资助项目(2006AA100311).

Effects of recombinant antimicrobial peptides on growth and immunity in tilapia (GIFT)

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1. Institute of Oceanology, Chinese Academy of Sciences, 2. Graduate University, Chinese Academy of Sciences,

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(10.68 g±0.53 g 。通过研究了饲料中添加抗菌肽对吉富罗非鱼幼鱼的生长性能、免疫指标以及攻毒实验的影响。结果显示当添加量为肝脏的超氧化物歧化酶与血清中溶菌酶活性较对照组显著降低添加氟苯尼考组较对照组能显著提高红细胞总数 <0.05), 20 mg/kg

Abstract:

Antimicrobial peptides have attracted considerable attention because of their potential use for therapy and prophylaxis. We evaluated the effects of dietary supplementation with recombinant antimicrobial peptide on growth, immunity, and performance in the protest test in 10.68g±0.53g. The fish were divided into six treatment groups and fed experimental diets containing cell numbers, and catalase activity were significantly higher in the groups supplemented with 5 and 10 mg/kg compared with the control. The specific growth rate was highest in the group given 5 mg/kg RAP. Liver lysozyme activity were significantly lower in the group given 50 mg/kg RAP than in the control. Supplementation with 100 mg/kg florfenicol increased the number of red blood cells, but had no effect on the other indexes. Following infection with , the death rate was significantly lower in groups fed between 5–20 mg/kg RAP than in the control. The survival was highest in the group fed 5 mg/kg. Our results suggest that dietary supplementation with appropriate levels of antimicrobial peptide improves growth, immunity, and performance in the protest test . However, increasing the dose can lead to negative effects on growth and enzyme activity. Therefore, we recommend that supplementation should not exceed 20 mg/kg. Our results provide insight into the proper application of recombinant antimicrobial peptides to

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姜珊,王宝杰,刘梅,蒋克勇,宫魁,王雷.饲料中添加重组抗菌肽对吉富罗非鱼生长性能及免疫力的影响[J].中国水产科学,2011,18(6):0-
JIANG Shan, WANG Baojie, LIU Mei, JIANG Keyong, GONG Kui, WANG Lei. Effects of recombinant antimicrobial peptides on growth and immunity in tilapia (GIFT)[J]. Journal of Fishery Sciences of China,2011,18(6):0-

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在线发布日期: 2011-11-12
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