on growth, digestive enzyme activity, and non-specific immunity in hybrid sturgeon ( ♀) juveniles. The hybrid sturgeon fingerlings (=225, initial average weight: 10.34 g±0.19 g) were randomly assigned to 5 groups (3 replicates/group, =15 per replicate) that were fed one of five diets containing 0 (control), 0.05% (group ), or 0.5% (group for 30 d. Growth was improved in hybrid sturgeon fed a diet containing 0.25% . Weight gain and the specific growth ratio increased by 54.31% and 28.61%, respectively, compared with the control group (<0.05). The feed conversion ratio was 36.02% lower than in the control group (<0.05). The activities of amylase, lipase, and protease were higher in the intestine in all groups compared with the control group. Furthermore, activity was higher on day 15 than on day 30. Digestive enzyme activity was highest in group and was significantly higher than in the control group (<0.05). Similarly, lysozyme, superoxide dismutase, and alkaline phosphatase activity and total antioxidant capacity were higher in group III than in the remaining groups on day 15 (<0.05). The indices of non-specific immunity were lower on day 30 than on day 15 in group III and were not significantly different from the control group to the diet increases digestive enzyme activity and non-specific immunity and promotes the growth of hybrid sturgeon juveniles. The benefits were most pronounced at a level of 0.25% with repeated supplementation every 15 d.