llerian hormone (AMH), also known as Mllerian inhibiting substance (MIS), is a glycoprotein belonging to the transforming growth factor superfamily, which plays a major role during reproductive development in . The open reading frame (ORF) of this gene spans a region of 1 563 bp and codes 520 amino acids. ooth tongue-sole and mRNA expression in 14 tissues of the half-smooth tongue-sole. Expression level was highest in male and neo-male gonads, followed by the blood, skin, and brain. Furthermore, in contrast with normal offspringthe gonad of male and neo-male non-normal offspring exhibited an increased in expression, but there was no change in females. This suggests thatgene is required for sex reversal.