, is one of the most economically important farmed shrimpspecies worldwide, which has the higher yields and lower production cost, and it is mainly distributed from theGulf of California to the Pacific coastal waters of northern Peru. In 1998, was introduced to China,but the long-term sustainability of white shrimp farming is currently under threat because of variation in size ,vulnerability of farmed stocks to disease and many other germplasm recession-related problems. The current statusof white shrimp aquaculture highlights the need for a systematic stock improvement program to improve economicallyimportant traits. The cultivation of strongly resistant, fast growing new shrimp strains is key to maintainingsustainable development of the breeding groups to improve growth, disease resistance, and other quantitativetraits that yield genetic improvement. Although the domestic germplasm mainly comes from anAmerican source, there has been substantial genetic improvement of , including production of newstrains such as “in section No. 1, ” “ZTE No. 1, ” “Kehai No. 1, ” and “Gui Hai No. 1, ” which were obtained fromdistant groups by hybridization. Heterosis can effectively improve growth potential and increase production,which is one of the most important goals of animal and plant breeding. Crossbreeding has been used in aquacultureto exploit hybrid vigor in crossbred offspring that show better performance and increased fitness compared withtheir purebred parents. In the present study, we used genetic resources from different geographical strains of whiteshrimp from Miami, Hawaii, and Thailand in a complete diallel cross (Griffing I). In this study, we analyzed theeffect of heterosis on growth rate and body weight at parental- and hybrid-strain juveniles, adults, and reserve seedstages. The results showed that the ranges of least squares means of different mating combinations among thesestages were 5.86–12.15 g, 14.79–28.82 g, and 38.25–54.74 g, respectively, and the ranges of growth rate were3.40–5.70%/d, 1.11–2.56%/d, and 0.33–0.68%/d, respectively. Least squares means of hybrid strains were higherthan those of inbred strains. Heterosis analysis showed positive mid-parent heterosis and heterobeltiosis for bodyweight of hybrids with a diminishing trend over time. The highest heterosis occurred in hybrid offspring that werecrosses of female individuals of the Miami population with male individuals of the Hawaiian population. At eachgrowth stage, least squares mean of offspring of the Miami population and average of the parents were higher thanthose of the average of all 3 parent populations. Increase in proportion of Miami and Hawaiian parents when producingcrosses will help improve offspring growth performance. Our study provides theoretical basis and technicalparameters for constructing a base breeding population of white shrimp in the future.