This paper addresses the spatiotemporal distribution characteristics of zooplankton abundance and seasonalchanges in fish egg and larval density based on data from four oceanographic surveys in Guangxi offshore waters in theNorthwest Beibu Gulf during the winter, spring, summer, and autumn of 2012. Additionally, the relationships between environmentalfactors, water masses, and, in particular, zooplankton were explored. The results revealed that zooplanktonabundances were 337.35 ind/m, and 14.78 ind/min the winter, spring, summer, and autumn,respectively. The zooplankton numbers between spring and summer, and between autumn and winter significantly changed,but remained steady between winter and spring, and summer between and autumn. The peak zooplankton abundance periodin this water body was winter, which occurs a season before that in the East China Sea. In the investigation area,, an economically important fish species, exhibited obvious seasonal distribution characteristics: Capturerates in winter and spring were higher than those in summer and autumn, which was consistent with the seasonal variationcharacteristics of zooplankton. High quantities of zooplankton in the winter and spring provided sufficient food to supplementfish populations and therefore provide a valuable resource for fish reproduction and growth. Northwest Beibu Gulf ismainly affected by coastal water, offshore current and mixed water. Coastal water is composed of sea water and mixedwater that is diluted by terrestrial runoff to the sea. A high salinity offshore current that is composed of offshore water runsinto the Beibu Gulf from the bay mouth. Mixed water composed of coastal and offshore water converges in the continentalshelf area. In the winter and spring, zooplankton distribution characteristics were similar; higher numbers of zooplanktonwere recorded in gulf and coastal waters than in inshore waters. However, zooplankton abundance in inshore waters wassignificantly higher than those in gulf and coastal waters during the summer and autumn. Sea water and mixed water in thisarea are affected by seasonal changes in coastal waters; the dominant species succession consisted of warm temperate neriticspecies in spring, warm water offshore species in summer and autumn, and warm water neritic species in winter. The dominantspecies were in the winter, spring, and summer and autumn, respectively.The ecological adaptability of the main dominant species determined the spatial and temporal distribution of these species,which in turn determined the zooplankton distribution characteristics. The combination of internal (ecological adaptation) andexternal (seasonal environmental change) factors resulted in the zooplankton distribution variation observed in this study. Thesefactors also likely drove seasonal species succession in this area. Zooplankton are a vital food source for most fish species duringtheir larval periods. Variations in zooplankton distribution and quantity can be either directly or indirectly affected by fish ingestion,migratory and catch behavior, and feeding period. Fish egg and larval densities were 6.83 ind/m,and 0.20 ind/mfrom winter to autumn; seasonal trends were highly consistent with those of zooplankton. A strong positive correlationindicates that rich food sources of zooplankton facilitate both fish egg and larval development.