N₂O emissions from aquaculture activities are attracting increasing attention. This paper compares the results of experimental studies on N₂O emissions from aquaculture and estimation studies based on material balance, analyzes the state of nitrogen emission from different aquaculture modes, and constructs strategies to reduce N₂O emissions. The results showed that the N₂O emission coefficients measured in actual culture processes were lower than those in wastewater treatment processes. The efficiency of nitrogen utilization and the pathways of the unused nitrogen from different farming modes were quite different. In addition, the nitrogen treatment approach of the recirculation aquaculture system was the closest to that of the wastewater treatment plant, but the recirculation aquaculture production accounted for a low proportion of the global aquaculture production. Additionally, being fed is not required during the production of approximately half of the aquaculture yield. Therefore, the results based on the N₂O emission coefficient of the wastewater treatment plant and the total N₂O emission of aquaculture production will be significantly larger. Currently, there is still a lack of basic research on the production of N₂O in aquaculture. Therefore, this paper does not establish relevant estimates. Future studies should conduct systematic research on the production of N₂O in aquaculture activities to provide theoretical support for the objective assessment of N₂O emissions from aquaculture activities.