Cephalopod species are well documented for fast growth rate, short life span, and high sensitiveness to their ambient marine environments. Energy accumulation is central to the life history of organisms, indicating their levels of energy reserves and resilience to ongoing environmental changes. In order to enhance our understanding of the adaptability of to its habitats, the energy density determination technique, coupled with the generalized additive model (GAM), was applied to investigate energy accumulation in the somatic and gonad tissues, in relation to oceanographic variables, in from the equatorial water of the eastern Pacific. The results showed that the soma energy of male and female individuals increased significantly with growth and development, and was mainly influenced by geographic latitude and sea surface temperature (SST). Significant differences in the gonadal tissue energy were found between immature and mature animals. The energy accumulated in the gonadal tissue was significantly related to the geographic latitude and longitude, SST, and chlorophyll-a concentration. These lines of evidence indicate that the somatic and gonadal tissues of in the equatorial water of the eastern Pacific continuously accumulate energy during the course of sexual maturation. There was tissue-specific energy accumulation in relation to ambient environments, in which the soma energy was significantly correlated with SST. Not only does SST significantly influence energy accumulation in gonadal tissues, but also chlorophyll-a concentration is an important environmental variable influencing gonadal tissue energy. Also, gonadal energy accumulation in female animals showed an obvious increasing trend with the westward geographic longitudes, indicating that the life history of includes offshore feeding migration.